PrenatalSafe® is a non-invasive prenatal test that detects chromosomal abnormalities by analyzing cell-free fetal DNA from a pregnant woman’s blood sample. PrenatalSafe® Karyo Plus represents an evolution of the PrenatalSafe® Karyo test. In addition to the possibility of detecting aneuploidies and structural chromosomal abnormalities affecting each chromosome, with results very similar to the determination of the fetal karyotype performed with invasive prenatal diagnostic techniques, PrenatalSafe® Karyo Plus makes it possible to identify the presence in the fetus of submicroscopic structural chromosomal abnormalities, such as 9 of the most common microdeletion syndromes. This test also includes fetal sex determination (optional).
\n <\/p>\n
Microdeletion syndrome<\/p>\n
Chromosomal Region<\/p>\n
Prevalence (at birth)<\/p>\n
DiGeorge Syndrome<\/p>\n
22q11.2 deletion<\/p>\n
1\/2.000 – 1\/4.000<\/p>\n
Cri-du-chat Syndrome<\/p>\n
5p15.3 deletion<\/p>\n
1\/15.000 – 1\/50.000<\/p>\n
Prader-Willi Syndrome<\/p>\n
15q11.2 deletion<\/p>\n
1\/25.000<\/p>\n
Angelman Syndrome<\/p>\n
15q11.2 deletion<\/p>\n
1\/10.000 – 1\/20.000<\/p>\n
1p36 deletion Syndrome<\/p>\n
1p36 deletion<\/p>\n
1\/5.000 – 1\/10.000<\/p>\n
Wolf-Hirschhorn Syndrome<\/p>\n
4p16.3 deletion<\/p>\n
1\/20.000 -1\/50.000<\/p>\n
Jacobsen Syndrome<\/p>\n
11q23-q24.3 deletion<\/p>\n
1\/100.000<\/p>\n
Langer-Giedion Syndrome<\/p>\n
8q24.11-q24.13 deletion<\/p>\n
1\/200.000<\/p>\n
Smith-Magenis Syndrome<\/p>\n
17p11.2 deletion<\/p>\n
1\/15.000 – 1\/25.000<\/p>\n
\nPrenatalSafe® Karyo Plus is not indicated for dichorionic twin pregnancies.
\nPrenatalSafe® Karyo Plus can be integrated, for free, with RhSafe® test, a non-invasive prenatal exam that, analyzing the fetal DNA isolated from a blood sample of the mother to be, allows to determine fetal Rh(D) Factor. RhSafe® test is optional, and is performed for free (on request) in Rh(D) negative pregnant women, with a Rh(D) positive male partner.
\n <\/p>\n","protected":false},"excerpt":{"rendered":"
PrenatalSafe® is a non-invasive prenatal test that detects chromosomal abnormalities by analyzing cell-free fetal DNA from a pregnant woman’s blood sample. PrenatalSafe® Karyo Plus represents an evolution of the PrenatalSafe® Karyo test. In addition to the possibility of detecting aneuploidies and structural chromosomal abnormalities affecting each chromosome, with results very similar to the determination of […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[35404,35025,33520,33570,33603,33569,33548,35099],"tags":[],"class_list":["post-12539","post","type-post","status-publish","format-standard","hentry","category-24-chromosomes_en","category-9-microdeletions_en","category-analisi_en","category-gynecology_en","category-ngs_en","category-prenatal-diagnosis_en","category-prenatalsafe_en","category-structural-chromosome-abnormalities_en"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.laboratoriogenoma.eu\/en\/wp-json\/wp\/v2\/posts\/12539","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.laboratoriogenoma.eu\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.laboratoriogenoma.eu\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.laboratoriogenoma.eu\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.laboratoriogenoma.eu\/en\/wp-json\/wp\/v2\/comments?post=12539"}],"version-history":[{"count":0,"href":"https:\/\/www.laboratoriogenoma.eu\/en\/wp-json\/wp\/v2\/posts\/12539\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.laboratoriogenoma.eu\/en\/wp-json\/wp\/v2\/media?parent=12539"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.laboratoriogenoma.eu\/en\/wp-json\/wp\/v2\/categories?post=12539"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.laboratoriogenoma.eu\/en\/wp-json\/wp\/v2\/tags?post=12539"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}